Scientific and traditional sources have explored or mentioned Kambo, particularly in the context of Kambo ceremonies in New Jersey and New York, in relation to: mood and emotional well-being (including stress, anxiety, and low mood), energy and vitality, circulatory and cardiovascular function, immune and inflammatory balance, detoxification and liver support, digestive and gut health, hormonal and reproductive balance, cognitive clarity and focus, physical stamina and recovery, addictive patterns and dependency, autoimmune and inflammatory responses, as well as skin, eye, and lymphatic support. Many individuals seeking these benefits often turn to a Kambo practitioner or the use of sapo for enhanced therapeutic effects.